Which came first? · Tricky
Which came first: Hershey's or the smallpox vaccine?
The smallpox vaccine came first, in 1798 (published). Hershey's followed 96 years later, in 1894 (founded).
- Second1894
Hershey's
company · foundedMilton Hershey founded his chocolate company in 1894, after starting out in caramels.
- First1798
The smallpox vaccine
medicine · publishedEdward Jenner published his smallpox vaccine in 1798; "vaccine" comes from the Latin word for cow.
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All which-came-first pairs · About Older Than You Think · Quiz games
Years from Wikidata, each checked against the item’s English Wikipedia article on 2026-10-18. A year stands for what its label says: a founding, a first patent, a premiere.